Sigma LifeScience

	► Sigma Life Science is a Sigma-Aldrich business that represents the Company’s leadership in innovative biological products and services for the global life science market and offers an array of biologically-rich products and reagents that researchers use in scientific investigation. Product areas include biomolecules, genomics and functional genomics, cells and cell-based assays, transgenics, protein assays, stem cell research, epigenetics and custom services/oligonucleotides. Sigma Life Science also provides an extensive range critical bioessentials like biochemicals, antibiotics, buffers, carbohydrates, enzymes, forensic tools, hematology and histology, nucleotides, amino acids and their derivatives, and cell culture media.

Custom DNA Probes	► Whether your application is genotyping, gene expression, pathogen detection, or other, Sigma's wide selection of reporter and quencher dyes for quantitative PCR (qPCR) probes will support all real time and end-point detection chemistries.

Custom DNA Oligos	► Sigma offers you an innovative line of custom oligonucleotides for your research. As always, every custom DNA oligo is deprotected, desalted, and undergoes mass spec QC.

OligoArchitect™ Primer and Probe Design Solutions	► Sigma is pleased to offer OligoArchitect for all of your primer and probe design requirements. OligoArchitect includes both our complimentary online design tool and our unique consultative service.

Probe-based Quantitative Real-Time PCR	► Sigma’s JumpStart™ Taq ReadyMix™ is available in various formulations and contains all necessary components for qPCR—simply add the fluorescent detection chemistry (probes), primers, and template. The JumpStart Taq DNA Polymerase features an antibody-based hot-start technology designed to minimize non-specific amplification.

SYBR® Green I-based Quantitative Real-Time PCR	► Sigma's JumpStart™ Taq ReadyMix™ is also available in various SYBR Green I formulations.

Reverse Transcription Quantitative Real-Time PCR	► Sigma’s one-step Quantitative RT-PCR ReadyMixes combine the advantage of M-MLV RT (Moloney Murine Leukemia Virus Reverse Transcriptase) and JumpStart Taq DNA Polymerase in a convenient ReadyMix designed for probe and SYBR-based assays.

qPCR Seminar Series	► Sigma-Aldrich is pleased to be able to bring you a series of webex seminars dedicated to qPCR. These presentations from international speakers cover the latest advances in qPCR techniques and practice.

Contact	Sigma-Aldrich Corporation 3050 Spruce Street St. Louis, MO 63103 Phone: (800) 521-8956 Fax: (800) 325-5052 Email: ContactSigma-Aldrich@sial.com