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► LGC Biosearch Technologies is a global leader in the design, development, and manufacture of custom oligonucleotides and associated reagents for the molecular diagnostics, research and applied markets. LGC Biosearch is ISO 9001:2008 and ISO 13485:2003 certified and provides best-in-class products for use in quantitative and end-point PCR utilizing its extensive portfolio of proprietary fluorophores (CAL Fluor®, Quasar® and Pulsar® dyes) and dark quenchers (the industry leading BHQ® (Black Hole Quencher®) dyes).  In addition, LGC Biosearch has IP relating to qPCR probe design (BHQplus® probes) and RNA FISH (Stellaris® assays) as well as expertise in other genomic-based applications including NGS.
In addition to basic R&D applications, LGC Biosearch has demonstrated expertise in fully assembled kits and in the cGMP manufacture of oligonucleotide components for molecular diagnostic assays.  LGC Biosearch is registered with the FDA (registration number 3003009052), and licensed by the State of California Department of Public Health (license number 72147) as a medical device manufacturer. As such, its GMP and Commercial Services manufacturing processes conform to all applicable requirements per 21 CFR Part 820 and ISO 13485:2003.

BHQnova™ Probes

► The most difficult qPCR applications demand double-quenched probes for optimum performance. BHQnova™ probes have improved quenching efficiency compared to traditional end-labeled probes, while also improving signal release upon amplification. BHQnova is most advantageous in longer probe designs, typically those over 25 bases, to boost the signal-to-noise ratio by overcoming the upper limit on sequence length.

For more product information, visit:

Multiplexing qPCR

Multiplex up to 5 targets using Biosearch Technologies’ CAL Fluor and Quasar dyes, which are brilliant dyes that emit signals from the UV to the IR.  They are compatible with most popular real-time PCR thermal cyclers and are efficiently quenched by the Black Hole Quencher dye series.  Try RealTimeDesign software in designing your next multiplexed qPCR assay.

Learn more by requesting a free multiplex guide:

RealTimeDesign™ Design Software

► RealTimeDesign™ software from Biosearch Technologies is a free, easy to use, yet powerful design application for real-time qPCR.  It offers both Express and Custom Modes to accommodate the different levels of control that assays may require.  The software links directly to NCBI to retrieve sequences according to accession number, and to confirm priming specificity.  Both novice and advanced users can use RealTimeDesign software to design assays for gene expression analysis, SNP genotyping, and multiplexed qPCR.

Use RealTimeDesign Software for free with registration:

Other Probe Formats

Dual-labeled BHQ® Probes
Molecular Beacons
Scorpions® Primers
Download our Fluorogenic Probes and Primers Brochure for more information

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For more information about Biosearch Technologies or any of Biosearch Technologies’ products, please contact:

Toll-free:  1.800.GENOME.1  (436.6631)    U.S./Canada Only

Tel:   +1.415.883.8400
Fax:  +1.415.883.8488

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