Freising,
10th April 2017 |
Dear
colleagues,
dear researchers,
dear company
representatives,
The great
international
interest in the previous qPCR dPCR & NGS Events from 2004 till 2015
with a constant audience of more than 500 participants from all over
the world motivates repeating the success next year in April 2017.
Hence the date for the 8th international Gene Quantification Event is
from 3rd to 7th April 2017. We broaden our focus in genomics
applications from quantitative RT-PCR, over digital PCR to the latest
Next Generation Sequencing technologies and the connected integrative
Big Data Analysis. As done in previous years, we offer a three day
scientific symposium with around 70 talks in two lecture halls.
Parallel to the scientific symposium an Industrial Exhibition will take
place where around 35-40 international companies will present their
newest qPCR, dPCR and NGS services, hardware and technologies. The
symposium will be followed by various 2-day PCR & NGS related
Workshops taking place April 6th and 7th powered by leaders in the
field.
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The
focus topics of the qPCR dPCR & NGS 2017 Gene Quantification Event
are:
Liquid
Biopsy, Integrative Big Data Analysis, Biomarker Signature … and beyond
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Event
location is the central lecture hall complex and the foyer at TUM School of
Life Sciences
(Technical University of Munich) in Freising Weihenstephan, Germany.
The TUM and the Biotech region around Munich are part of the largest Biotech
cluster in Europe (BioM),
representing more than 250 companies and academic institutions, located
close to the Munich airport (MUC) directly in the heart of Bavaria.
The
symposium is based on 72 lectures and 78
posters presented by international recognised experts in their
application
fields. The emphasis will be on unbiased, didactic and scientific
information
exchange. One third of the talks will be presented by invited speakers,
one
third of the speakers will be selected from the submitted abstracts and
one
third will be given to PCR and NGS company R&D representatives.
Various
poster sessions will be held in parallel in a separate poster
exhibition hall.
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Our publications:
All scientific
contributions (talks and poster abstracts) presented
at the symposium will
be published in a Supplement Issue
of Biomolecular
Detection and Quantification (Elsevier, ISSN 2214-7535).
All talks will be recorded and made public
in autumn 2017 via the www.eConferences.de
streaming
platform.
Please
have a look to the 2017 Event Promotion Trailer
Conference
Venue Address @ Google Maps
Foyer
Zentrales
Hörsaalgebäude
TU
München
School of
Life
Sciences
Campus
Weihenstephan
Maximus-von-Imhof
Forum 6
85354
Freising
- Weihenstephan
Germany
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As usual the qPCR
& NGS Event is structured in three parts: |
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1.
Symposium &
Poster Sessions & Confirmed Speakers
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April
3-5 2017
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2.
Industrial
Exhibition with around 40 companies
The Exhibition is
fully booked! |
April
3-5 2017 |
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3.
PCR & NGS
Application Workshops
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April
6-7 2017 |
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Promotion Trailer qPCR dPCR & NGS 2017
Follow 280
talks from previous events
on streaming
server www.eConferences.de |
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Keynote
Lectures:
RNA
capture sequencing enabled liquid biopsy screening.
JO VANDESOMPELE
Prof. at Center for Medical Genetics Ghent, Ghent University, Ghent,
Belgium; Biogazelle, Technologiepark 3, B-9052 Zwijnaarde, Belgium
Why
are we still using qPCR for the quantification of nucleic acids?
STEPHEN A. BUSTIN
Professor of Molecular Medicine, Postgraduate Medical Institute,
Faculty of Health, Social Care & Education, Anglia Ruskin
University, UK
Extracellular
vesicles and their potential as biomarkers and therapeutics.
JAN LÖTVALL
Prof. at Krefting Research Centre, Department of
Internal Medicine and
Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg,
Gothenburg, Sweden
Data
science and network modeling in biomedicine.
FABIAN THEIS
Prof. PhD, Institute of Computational Biology, Helmholtz Zentrum
München, Neuherberg, Germany
Unprecedented
accuracy when using digital PCR.
JIM HUGGETT
PhD, Science Leader, Nucleic Acid Metrology, LGC & Senior Lecturer,
Analytical Microbiology, University of Surrey, UK
Cancer-specific
long non-coding RNAs as novel biomarkers and targets for therapy.
PIETER MESTDAGH
Prof. at Center for Medical Genetics, Ghent University, Cancer Research
Institute Ghent, Ghent University, Belgium
In
silico functional analysis of microRNA : Towards the characterisation
of miRNAs as biomarkers.
ARTEMIS HATZIGEORGIOU
University of Thessaly, Hellenic Pasteur Institute, Ampelokipi, Athens,
Greece
Ultrasensitive
mutation detection in liquid biopsies using SiMSen-Seq.
ANDERS STAHLBERG
Prof. and Senior Scientist, Sahlgrenska Cancer Center, University of
Gothenburg, Sweden
Validation
of qPCR assays.
MIKAEL KUBISTA
Prof. of Biotechnology, BTU, Czech Academy of Sciences &
TATAA Biocenter, Sweden
=>
All Confirmed Speakers
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Symposium
Talk
& Poster sessions:
Main
topic:
Liquid
Biopsy & Circulating Nucleic Acids
The capture of whole,
circulating tumor cells (CTCs) was the initial focus of liquid biopsy.
Today it includes the collection of cell-free nucleic acids (cell free
DNA
& RNA) and all type of micro-vesicles
(incl. exosomes), to provide useful information on the physiological
status.
The session includes any kind of circulating
nucleic acids families (DNA, RNA, small RNAs, microRNAs, piRNAs, and
long
ncRNAs). One focus will be on exosome or micro-vesicles isolation &
purification, amount & size quantification, and biomarker
characterisation
techniques, including intra-cellular, membrane bound protein or lipid
markers.
Main
topic:
Advanced
Molecular Diagnostics
This session is
focusing on the application of highly sophisticated methods,
application and
algorithms to discover, detect, and validate molecular diagnostic
marker
or biomarker
signatures. A special focus is lying on the integrative analysis of
multi-level biomarkers, e.g. microRNA –
mRNA, integrative analysis of genomic, proteomic, metabolomic and
phenotypic
markers.
Main
topic:
Integrative Big Data Analysis
The data analysis in
RT-qPCR expression profiling and NGS experiments is still challenging
and time
consuming. It is well known, that a lot of error is introduced by wrong
experimental study design, poor sample and group normalisation or
differential
gene expression analysis. This session is focusing on the application
of
useful new algorithms & data analysis
methods to getter better and more reliable results, e.g. R-based
freeware,
and software applications for data mining and comparison, calculation
of
relative expression, for any kind of nucleic acid (mRNA, microRNA,
piRNA). One focus
of this session will be the integrative
analysis of multi-level biomarkers (mainly the microRNA-mRNA),
mathematical
modelling, multivariate expression profiling, statistics in NGS and
qPCR,
multiple regression analysis, 3D data
visualization, and more.
Main
topic: Biomarker Signatures
A session about the
discovery, detection and validation of molecular biomarkers:
diagnostic, prognostic or therapeutic markers
on DNA, RNA, microRNA or small RNA,
metabolome and proteome level (e.g. disease markers, cancer or
stem-cells
markers, tissue specific markers, differentiation markers, methylation
markers). New assay systems will be presented like high throughput
proteomics
(MS based proteome map), PLA (Proximity Ligation Assay) or PEA
(Proximity
Elongation Assay).
Digital PCR
Digital PCR (dPCR)
can be used to directly quantify and clonally amplify nucleic acids
including
DNA, cDNA, mRNA, microRNA or any other small-RNA species. It allows a
more
reliable collection and highly sensitive
measurement of nucleic acid amounts, applications in copy number
variants,
point mutations in molecular diagnostics.
Non-coding RNAs --
microRNA, isomiRs, small RNAs, long
non-coding RNAs
This session is
dedicated to the family of non-coding RNA and its RNAi mechanism and
applications. A new focus will be on the identification and the data
analysis
& modelling of new isomiR biomarkers
and long non-coding RNAs. RT-qPCR or
small RNA Seq technologies to quantify small & long non-coding RNAs
and other
classes of small RNAs, like piRNAs.
Further siRNA knock down applications, microRNA targets and microRNA
precursors, new siRNA manipulation, etc. will be presented.
MicroGenomics &
Single-Cells Diagnostics
Focus in this session
is on micro-genomics, the application of molecular methods to detect
biomarkers
in a minimal amount of tissue or any biological matrix. New
applications in single-cell biology will be presented: isolation,
separation, characterisation technologies, laser micro dissection,
capturing of
circulating tumour cells (CTC),
pre-amplification techniques, sub-cellular PCR, micro-manipulation of
cell
clusters, cellular micro injection, single-cell handling, FACS sorting
and
spotting.
Next Generation
Sequencing (NGS)
NGS applications
offers new holistic analysis of any kind of nucleic acid, to
investigate the Genome,
Exome, Epigenome, Transcriptome and Splicome (total RNA, microRNA,
small RNA
Seq, long ncRNA), CHIP purified nucleic acids, etc.
Various NGS sub-sessions will be
presented:
- NGS overview talks - information technology in the
era
of NGS & diagnostic applications
- Pre NGS -
sample preparation & setup & library
generation
- NGS – new
sequencing technologies (e.g. in-situ, single
molecule and pore sequencing)
- NGS – data
analysis (data management, mapping,
alignment algorithms, data de novo assembly )
Molecular
Diagnostics in Life Science
This session is
dedicated to molecular diagnostics in Life Science, with focus on
Agriculture, Veterinary Medicine, Food and
Environmental Science, which is the major research focus at the TUM
School
of Life Science Campus Weihenstephan. All applications of highly
sophisticated
quantification methods, field application or algorithms to research the
wide
field of agro-veterinarian or life science are very welcome.
MIQE & QM &
Standardisation Strategies in
Molecular Diagnostics
This session is
focusing on standardisation strategies and quality management in
molecular diagnostics. The goal is to
guarantee better and more valid results.
Of special interest in the context of qPCR or dPCR are the MIQE
guidelines (minimum information for publication of
quantitative real-time PCR experiments). Following these guidelines
will
encourage better experimental practice, allowing more reliable and
unequivocal
interpretation of qPCR and dPCR results.
The
scientific
organization
is managed by international well-known
scientists:
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Scientific
board:
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Stephen Bustin
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Prof. of Molecular
Medicine, Faculty of Health, Social Care & Education, Anglia Ruskin
University, UK
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Mikael Kubista
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Prof. of Biotechnology, BTU,
Czech Academy of Sciences & TATAA Biocenter, Sweden
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Vladimir
Benes |
PhD, Head of the
Genomics Core Facility at EMBL, Heidelberg, Germany
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Jim
Huggett |
PhD, Science
Leader, Nucleic Acid Metrology, LGC, London Twickenham, UK |
Justin O’Grady |
PhD, Medical
Microbiology, University of East
Anglia, UK |
Jo
Vandesompele |
Prof. at
the Center of Medical Genetics, University of Ghent, Belgium
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Michael W. Pfaffl
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Prof. of Molecular Physiology,
TUM School of Life Sciences, Weihenstephan,
Germany
Scientific coordinator of the Symposium and the Application
Workshops qPCR-dPCR-NGS-2017@wzw.tum.de
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Event
organization:
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Sylvia Pfaffl, bioMCC,
85354 Freising Eventmanagement@bioMCC.com
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We are
looking
forward to meeting you in April 2017 at the Symposium in
Freising-Weihenstephan
Michael W.
Pfaffl
Symposium Chair
Important
dates:
Abstract Submission Deadline:
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Abstract submission deadline
is 31st January 2017
Please
register
using
the
Internet based ConfTool registration & submission platform =>
Registration.qPCR-dPCR-NGS-2017.net
- Register as ConfTool User
=>
NEW USER => Create new
account
- Register as symposium PARTICIPANT
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for the
symposium
and/or workshops
- Submit
Contribution =>
submit
your TALK and/or POSTER abstract(s)
- Please
indicate in which Session
you want to present either a POSTER or give an TALK
Presentation via MS PowerPoint
- The
abstract should be a one-page document based on unpublished material
and
written in good standard English.
- The text should clearly state
objectives,
methodology, results, and conclusion. Simple tables and graphs are
allowed.
- All scientific
contributions (talks and poster abstracts) will be published in an
Supplement Issue of Biomolecular
Detection and Quantification (Elsevier, ISSN 2214-7535).
- Please note -- All
talks will be recorded!
In summer 2017
the recorded
talks
will be published on www.eConferences.de
Until
autumn 2017 the recorded tallks are password
protected
and only accessible for Symposium and Workshop participants.
- All talks will be recorded and made public
in autumn 2017 via the www.eConferences.de
streaming platform.
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Symposium:
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- The
official conference and workshop language is ENGLISH
- No
simultaneous
translation
will
be provided.
- All oral presentations, posters and
abstracts must be presented in English
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Poster Layout:
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- The
official conference and workshop language is ENGLISH
- All oral presentations, posters and
abstracts must be presented in English
- Until
autumn 2017 the PDF
download of the poster contributions are password
protected
and only accessible for Symposium and Workshop participants.
- Poster
will be
DIN A0 (portrait format
=> 120
cm/48
inch high x 90 cm/35 inch wide)
- Presentation
of every communication at the Conference is subjected to formal
registration
of at least one co-author.
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Symposium Talks:
(each
talk 30 min)
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- Monday
3rd of
April 2017 10:00 a.m.
to
6:00 p.m.
- Tuesday
4th of April 2017
8:30 a.m.
to 6:30 p.m.
- Wednesday 5th of April
2017
8:30 a.m.
to 5:00 p.m.
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Industrial
Exhibition
The industrial
exhibition
will be held during the Symposium from 3-5
April 2017 in the
foyer of the central lecture hall complex
(green frame) and in two side rooms S1 and S2 (blue frame).
According to the booth location we have around 30-40 booth in different
prize categories. They are all located around the central lecture halls
H14 and H15
which fits up to 650 people. Event location is the
central lecture hall complex and the foyer at TUM School of Life Sciences
(Technical University of Munich) in Freising Weihenstephan, Germany.
The TUM and the Biotech region around Munich are part of the largest Biotech
cluster in Europe (BioM),
representing more than 250 companies and academic institutions, located
close to the Munich airport (MUC) directly in the heart of Bavaria.
For
booth reservations and providing further details about the industrial
exhibition, e.g.
exhibition contract, technical management, stand allocation, electronic
installations, internet connection (W-LAN), etc. we are pleased to
answer your questions. For details about sponsoring opportunities
please contact
our organisation team, headed by Sylvia Pfaffl (bioMCC, Germany) Eventmanagement@bioMCC.com
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