 |
 |
|
|
|
 |
Short company profile ► Since 1990, TIB MOLBIOL has been providing custom oligonucleotides to a growing number of customers worldwide, ranging from life science research, medical diagnostics over product quality assessment to environmental analysis. Being one of the first suppliers of synthetic DNA in Europe, we not only have set industry standards for quality and service, but continue to lead in fulfilling your demanding requirements for high quality products and services. Our development and production are certified after ISO 9001 and ISO 13485 (medical devices). |
|
|
|
| Oligonucleotides | ►
Oligonucleotides
are the most important tools in genomic research and molecular
diagnostics, and AntiSense oligonucleotides are also used as
therapeutics. PCR in particular has revolutionized the molecular
biology laboratory and has triggered an explosive number of novel and
exciting applications. A central feature of our custom synthesis is our
awareness of the individuality of our products, respecting individual
needs and requirements - our product is the 'individual oligo'. |
| Fluorescence | ► Fluorescence. TIB
MOLBIOL offers a broad spectrum of fluorophore labeled products
spanning the visible spectrum from UV to IR, including the classical
ABI dyes, Cyanine dyes (GE Healthcare), BODIPY dyes (Molecular Probes),
MegaStokes dyes (Dyomics), LightCycler® dyes (Roche Diagnostics),
BHQ
and BBQ quenchers, and many other dyes. |
| Real-Time PCR | ► Real-Time PCR with
TaqMan®, Molecular Beacons, SimpleProbe®, HybProbe® probes
or Scorpion
primers. TIB MOLBIOL manufactures DNA and LNA probes for the use in
Real-Time PCR quantification and genotyping. LNA-based probes strongly
increase specificity and sensitivity of Real-Time PCR assays. Synthesis
of Molecular Beacon probes under license of PHRI, SimpleProbe® and
LightCycler® hybridization probes under license of Roche
Diagnostics,
Scorpion primers under license of DxS, and IVD use TaqMan® probes
under
license of Roche Molecular Systems. |
| Assay Design in Real-Time PCR. | ► Assay Design in Real-Time PCR.
We at TIB would be more than happy to lend our assistance in the design
of suitable primers and probes for either product quantification or
nucleotide polymorphism detection with Real-Time PCR. Our design
department works on new assays, either based on established protocols
or starting from new targets. We are prepared to evaluate systems in
our application and research laboratories. For some applications we
have established our own system or are aware of other existing or
published assays. Customer data, including sequences and projects
involved, are treated strictly confidential. Please contact design@tib-molbiol.de TIB MOLBIOL has designed more than 20,000 customer-specific assays within the last 14 years. |
| LightSNiP Assays | ► LightSNiP Assays. Since
2007 we provide SimpleProbe® based ready-to-use assays for the SNP
analysis of any Genbank-listed polymorphism (ordered by rs-number). |
| LightMix® kits | ► LightMix® kits
represent our product line of Real-Time-PCR kits designed to be used
with the Roche Diagnostics LightCycler® instruments, including
products
for the detection of pathogens (eg. atypical pneumonia, InfA H5N1,
H1N1, sexual transmitted diseases, fungi), cancer related tests (k-ras,
AML-ETO, PML-RAR) and many genotyping tests (MTHFR, HFE, lactose
intolerance). |
| LightMix® Diagnostic Kits | ► LightMix® Diagnostic Kits (CE-IVD
marked kits).
The k-ras codon 12/13 mutation detection kit is our first CE-labeled
product – intended for the analysis of tumor samples for selection of
treatment with EGF antibody based therapeutics. |
| DNA Chips | ►
DNA Chips. For information about our exciting low-cost chip
technology please contact: info@chipron.com |
| Contact |
TIB MOLBIOL Syntheselabor GmbH Eresburgstraße 22-23 12103 Berlin Contact Olfert Landt Phone +49-(0)30-787994-55 Fax +49-(0)30-787994-99 Email dna@tib-molbiol.de design@tib-molbiol.de Internet www.TIB-MOLBIOL.com |
| Collaborations | Bio-Rad Inc. Centro Biotecnologia Avanzate, Genova Charité, Berlin Chemicell GmbH, Berlin Chipron GmbH, Berlin Dyomics GmbH, Jena DRFZ, Berlin Epigenomics AG, Berlin Eppendorf AG, Hamburg Exiqon A/S, Vedbaek GenExpress GmbH, Berlin Merck KG aA, Darmstadt Microbiologia, Genova Mayo Clinic, Rochester Replicon GmbH, Berlin Roche Diagnostics GmbH |
|
|
|
|
|
|